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The landscape of actionable genomic alterations in lung adenocarcinomas in India

Sapien Biosciences is excited to share our recently published article, titled “The Landscape of Actionable Genomic Alterations in Lung Adenocarcinomas in India,” in Frontiers in Genetics, section Genetics of Common and Rare Diseases. Our retrospective study, involving 53 Indian Lung Adenocarcinoma patients and utilizing a targeted NGS panel of 46 cancer-relevant oncogenes, revealed pathogenic or […]

Timeline of Precision Medicine in Breast cancer

The timeline of breast cancer care and therapy is marked by significant milestones that have transformed patient outcomes and the way we approach this devastating disease as shown in the figure here. From the pioneering mastectomy procedures of the late 19th century to the development of targeted therapies specifically blocking the drivers of breast cancer […]

Staging of Breast Cancer is Important

Advancements in #tumor biology and prognostic #biomarkers, such as the estrogen receptor (ER), progesterone receptor (PR), HER2/neu, and Ki-67, have empowered clinicians to understand why patients with similar stages have significantly different outcomes. The 8th edition of the American Joint Committee uses nine stages (0, IA, IB, IIA, IIB, IIIA, IIIB, IIIC, and IV) based […]

Matched Plasma and Tumor blocks Available from Consented Cancer Patients

Sapien’s #biorepository is expanding with the collection of fresh blood from cancer patients prior to surgery, with informed consent. The collection covers all organs, including #Breastcancer (>320 cases). The blood is processed to #plasma and #PBMCs or cell pellets. Matched #FFPE tumor blocks are also available. With 6 sites now, the #biobank is growing rapidly […]

Sapien team at Grace Cancer run

The Sapien #biobank #Hyderabad team showed up with enthusiasm at the Grace Cancer Foundation fundraising event. Our team, along with family and friends, participated in the walk/run with full josh and walking shoes on. The well-organized event made it even more enjoyable.

Age distribution

Studies have shown that the risk for having breast cancer is due to a combination of factors. One of the main factors that influences the incidence of breast cancer is age, with the highest incidence rates being in older people. Most breast cancers are found in women who are 50 years or older. The American […]

Risk factors associated with breast cancer

Several risk factors are implicated in developing #BreastCancer in young women. Factors associated with lifestyle choices, such as physical inactivity leading obesity, excessive alcohol consumption and smoking; genetic risk factors involving mutations of breast cancer susceptibility genes such as #BRCA1 and #BRCA2; reproductive risk factors, such as age of menstruation onset, menopause can contribute to […]


Breast Cancer (BC) has surpassed lung cancer as the leading cause of cancer incidence in the world, with an estimated 2.3 million new cases, representing 11.7% of all cancer cases, with women bearing the brunt of it.In India, as per Globocan 2020 data, BC accounted for 13.5% (178,361) of all cancer cases and 10.6% (90,408) […]

October is Breast Cancer Awareness Month

Sapien has been actively collecting FFPE blocks, blood and data from #breastcancer patients in India. With over 18,000 Indian breast cancer cases from 9 cancer hospitals, Sapien has collated demographic and diagnostic datasets to aid in the fight against #breastcancer. Treatment, outcomes, genomic, biomarker and imaging data is being added to the #biobank, making early detection and optimal treatment […]