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Recurrence in Kidney Cancer

Kidney cancer most often spreads to lungs and bones, but it can also spread to brain, liver, and other organs. As it has no symptoms early on, it can spread before you even know you have it. Smoking tobacco doubles the risk of developing kidney cancer. Prevention of metastatic kidney cancer can be done by quitting smoking, maintaining a healthy body weight & eating a diet high in fruits & vegetables & low in fat. If cancer has not spread far, surgery may be a cure. If it has spread to other organs, then treatment like targeted therapy and Immunotherapy will be recommended.

 

 

Treatment for Kidney Cancer

Kidney cancer is most often treated with Surgery, Chemotherapy, Targeted therapy, Immunotherapy, Radiation therapy or combination of these treatments. Treatment options and recommendations depend on several factors, including the cell type and stage of cancer, possible side effects and the patient’s preferences and overall health. For most kidney cancers, surgery is the initial treatment. The goal of surgery is to remove the tumor while preserving normal kidney function. The type of surgery done to remove the tumor is Radical Nephrectomy & Partial Nephrectomy.

Metastatic Lung Cancer-Finding cure starts with awareness

Having lung cancer or a history of lung cancer, is the cause for lung cancer metastases. Cancer that metastasizes to the lungs is a life-threatening condition that develops when cancer in another area of the body (primary organ such as breast), spreads to the lung. Prevention of metastatic lung cancer can be done by avoiding the risk factors of primary lung cancer such as smoking or chewing tobacco, or prompt and successful treatment of your primary cancer. Awareness, early detection and timely treatment are vital for preventing the spread of lung cancer.

Sapien’s samples and real world data enables validation of a new Indian breast cancer test with high concordance to OncotypeDx test

In 2014, Sapien partnered with Oncostem Diagnostics to provide our curated breast cancer FFPE blocks and RWE 5 years treatment and recurrence outcome data to enable the validation of a new test to accurately determine the risk of recurrence in early stage breast ca patients. A key goal of the test was to identify patients at low risk that could avoid chemotherapy and its side-effects, a major benefit to #cancerpatients (see Sapien referenced in this & previous papers).

https://onlinelibrary.wiley.com/doi/full/10.1002/cam4.3495

It’s gratifying to see their first test, canAssist Breast for hormone positive breast cancer patients, perform equivalent to the gold standard Oncotype Dx test, a more expensive and higher TAT for Indian patients.

Our deep collection of matched FFPE blocks and longitudinal RWE data to enable precision medicine tests has continued to grow, both in breast cancer (>10,000 cases), and in #colorectalcancer, #lungcancer, #oralcancer, #kidneycancer, #ovariancancer #glioma #liver cancers. Contact us at  queries@sapienbio.com

The largest category of breast cancers are hormone receptor (HR) positive. These comprise 55-60% of all breast cancers globally as well as in India. Unlike triple negative breast cancer (TNBC), HR positive breast cancers respond well to personalized treatment with newer drugs and have a high chance of successful treatment and long-term survival even in advanced stages. Hence it is important to get them diagnosed and typed for HR positivity early on and tailor the treatment for each patient.

Lymphomas are cancers that develop in the lymphatic system. Typical symptoms start with fever, swelling of some lymph nodes, weight loss, tiredness. The affected lymph nodes could be in the neck, armpit, groin, tonsils, stomach, small intestine. Once a cancer begins in one part of the lymphatic system, it can spread rapidly to other lymph nodes so early diagnosis is important. Diagnosis is done by PET or CT scan and/or biopsy, as suggested by a doctor. The incidence of lymphomas is ~5-7% among all childhood cancers. It is 2-3 time more common in boys than in girls. In India, lymphoma was reported to be the 2nd most common cancer in young boys.

 

Resources:   https://www.worldchildcancer.org/, https://www.indiancancersociety.org/, https://www.acco.org/childhood-lymphomas/, https://www.childrenwithcancer.org.uk/, https://curechildhoodcancer.org/, https://lymphoma-action.org.uk/types-lymphoma-lymphoma-children-and-young-people/lymphoma-children

September is Childhood Cancer Awareness Month. 30,000 children in India and 10 times that number worldwide develop cancer every year. There is a lack of awareness and timely diagnosis to treat them. Sapien will be sharing the Indian cancer data it has throughout September, starting with colorectal cancer.

Resources: https://www.worldchildcancer.org/, https://www.indiancancersociety.org/, https://www.childrenwithcancer.org.uk/, https://curechildhoodcancer.org/,