Tag Archive for: pediatriccancer

Our paper is out in Frontiers in Pharmacology

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Our paper on first ever reported establishment of a cell culture from a rare brain tumor (DIG glioma), is published in Frontiers in Pharmacology journal, with Impact factor of 4.5. Such primary cultures are very useful for drugdevelopment and phenotypic screening.

https://www.frontiersin.org/articles/10.3389/fphar.2022.778193/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Pharmacology&id=778193

Pediatric gliomas

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Individuals below the age of 18 years are susceptible to #pediatriccancer and so #pediatriccancerawareness is paramount. Many different treatment options are available including #radiotherapy, #chemotherapy, and surgery based on the type of #cancer and disease severity. Excellent follow up care both by family, #survivorship clinics and organizations such as Pediatric Brain Tumor Consortium, Pediatric Brain Tumor Foundation, and others will restore a healthy life to those affected.

American Brain Tumor Association, 

Children’s Brain Tumor Foundation

International Brain Tumour Alliance

A Kids’ Brain Tumor Cure Foundation (PLGA Foundation)

National Brain Tumor Society

Pediatric Brain Tumor Foundation

ABC2 (Accelerate Brain Cancer Cure)

Lymphomas are cancers that develop in the lymphatic system. Typical symptoms start with fever, swelling of some lymph nodes, weight loss, tiredness. The affected lymph nodes could be in the neck, armpit, groin, tonsils, stomach, small intestine. Once a cancer begins in one part of the lymphatic system, it can spread rapidly to other lymph nodes so early diagnosis is important. Diagnosis is done by PET or CT scan and/or biopsy, as suggested by a doctor. The incidence of lymphomas is ~5-7% among all childhood cancers. It is 2-3 time more common in boys than in girls. In India, lymphoma was reported to be the 2nd most common cancer in young boys.

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Resources:   https://www.worldchildcancer.org/, https://www.indiancancersociety.org/, https://www.acco.org/childhood-lymphomas/, https://www.childrenwithcancer.org.uk/, https://curechildhoodcancer.org/, https://lymphoma-action.org.uk/types-lymphoma-lymphoma-children-and-young-people/lymphoma-children

Kidney cancer rarely affects children. The most common one is Wilms’ tumor, also called nephroblastoma, that accounts for up to 95% of childhood kidney cancers, with most children being below the age of 5 years. It is a fast growing tumor that can spread (metastasize). It is usually treated by surgery, followed by radiation and chemotherapy. Commonly used chemo drugs are doxorubicin, vincristine and actinomycin D. Overall survival rates tend to be high (>90%), with favourable histopathology diagnosis and timely treatment.

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https://www.indiacancersurgerysite.com/wilms-tumor-treatment-india.html

September is Childhood Cancer Awareness Month. 30,000 children in India and 10 times that number worldwide develop cancer every year. There is a lack of awareness and timely diagnosis to treat them. Sapien will be sharing the Indian cancer data it has throughout September, starting with colorectal cancer.

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Resources: https://www.worldchildcancer.org/, https://www.indiancancersociety.org/, https://www.childrenwithcancer.org.uk/, https://curechildhoodcancer.org/,