HRR testing including BRCA1/2 can guide therapy in Ovarian Cancer
Specific types of DNA damage, such as mismatches during replication, single- or double-strand DNA breaks, can result in the activation of specific signalling and repair cascades such as homologous recombination repair (HRR) in normal cells to repair the damage. However, deficiencies in these repair pathways result in the accumulation of DNA damage, genomic instability, and […]
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